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Günter Emons Selected Research

Triptorelin Pamoate (Trelstar)

1/2008Increase of doxorubicin-induced apoptosis after knock-down of gonadotropin-releasing hormone receptor expression in human endometrial, ovarian and breast cancer cells.
10/2005GnRH-II receptor-like antigenicity in human placenta and in cancers of the human reproductive organs.
10/2005Analogs of GnRH-I and GnRH-II inhibit epidermal growth factor-induced signal transduction and resensitize resistant human breast cancer cells to 4OH-tamoxifen.
11/2004Gonadotropin-releasing hormone (GnRH) agonist triptorelin inhibits estradiol-induced serum response element (SRE) activation and c-fos expression in human endometrial, ovarian and breast cancer cells.
7/2004Antiproliferative effects of the GnRH antagonist cetrorelix and of GnRH-II on human endometrial and ovarian cancer cells are not mediated through the GnRH type I receptor.
5/2004Luteinizing hormone-releasing hormone (LHRH) inhibits apoptosis induced by cytotoxic agent and UV-light but not apoptosis mediated through CD95 in human ovarian and endometrial cancer cells.
5/2002Luteinizing hormone-releasing hormone induces JunD-DNA binding and extends cell cycle in human ovarian cancer cells.
3/2002Expression of gonadotropin-releasing hormone II (GnRH-II) receptor in human endometrial and ovarian cancer cells and effects of GnRH-II on tumor cell proliferation.
2/2002Expression of receptors for luteinizing hormone-releasing hormone in human ovarian and endometrial cancers: frequency, autoregulation, and correlation with direct antiproliferative activity of luteinizing hormone-releasing hormone analogues.

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Günter Emons Research Topics

Disease

46Neoplasms (Cancer)
06/2021 - 01/2002
30Breast Neoplasms (Breast Cancer)
12/2020 - 10/2004
23Ovarian Neoplasms (Ovarian Cancer)
01/2021 - 02/2002
21Endometrial Neoplasms (Endometrial Cancer)
01/2021 - 01/2002
11Triple Negative Breast Neoplasms
07/2019 - 01/2010
6Neoplasm Metastasis (Metastasis)
01/2021 - 12/2011
3Bone Resorption
09/2003 - 01/2002
2Carcinoma (Carcinomatosis)
01/2020 - 09/2003
2Pancreatic Neoplasms (Pancreatic Cancer)
01/2017 - 09/2011
2Pre-Eclampsia (Preeclampsia)
01/2013 - 09/2002
2Habitual Abortion (Recurrent Miscarriage)
10/2003 - 09/2003
1Osteoporosis
06/2021
1Primary Ovarian Insufficiency
06/2021
1Dementia (Dementias)
06/2021
1Cardiovascular Diseases (Cardiovascular Disease)
06/2021
1Endometrial Hyperplasia
01/2021
1Carcinosarcoma
11/2018
1Glioblastoma (Glioblastoma Multiforme)
01/2017

Drug/Important Bio-Agent (IBA)

34Gonadotropin-Releasing Hormone (GnRH)FDA Link
01/2021 - 01/2002
23LHRH Receptors (Gonadotropin-Releasing Hormone Receptor)IBA
01/2021 - 01/2002
12Estrogens (Estrogen)FDA Link
01/2021 - 01/2008
11lysine(6)-doxorubicin LHRHIBA
07/2019 - 09/2002
10Doxorubicin (Adriamycin)FDA LinkGeneric
06/2014 - 05/2002
10His(5)-Trp(7)-Tyr(8)- LHRHIBA
01/2013 - 03/2002
9Estrogen ReceptorsIBA
09/2020 - 07/2005
9Triptorelin Pamoate (Trelstar)FDA Link
01/2008 - 02/2002
8Progesterone Receptors (Progesterone Receptor)IBA
01/2018 - 01/2010
7Growth Factor ReceptorsIBA
01/2017 - 01/2002
6Pharmaceutical PreparationsIBA
10/2020 - 01/2008
5Protein Tyrosine PhosphatasesIBA
01/2017 - 01/2002
5cetrorelix (Cetrotide)FDA Link
07/2004 - 02/2002
4TamoxifenFDA LinkGeneric
09/2020 - 05/2005
4Estrogen Receptor Modulators (Antiestrogen)IBA
09/2020 - 04/2008
4DNA (Deoxyribonucleic Acid)IBA
01/2013 - 05/2002
4Caspase 3 (Caspase-3)IBA
05/2011 - 05/2004
3EnzymesIBA
12/2020 - 09/2002
3Estrogen Receptor alphaIBA
09/2020 - 11/2004
3Deoxyglucose (2 Deoxy D glucose)IBA
07/2019 - 01/2013
3PlatinumIBA
03/2016 - 09/2003
3afimoxifene (hydroxytamoxifen)IBA
11/2012 - 10/2005
3Cytotoxins (Cytolysins)IBA
01/2009 - 05/2004
3RANK LigandIBA
06/2008 - 01/2002
3NF-kappa B (NF-kB)IBA
01/2008 - 01/2002
3Oncogene Proteins (Oncogene Protein)IBA
02/2007 - 01/2002
3Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
02/2007 - 01/2002
3factor V LeidenIBA
10/2003 - 05/2003
2Hormones (Hormone)IBA
06/2021 - 04/2010
2GonadotropinsIBA
01/2021 - 11/2012
2Small Interfering RNA (siRNA)IBA
12/2020 - 07/2012
2GTP-Binding Proteins (G-Protein)IBA
09/2020 - 01/2018
2Cysteine (L-Cysteine)FDA Link
01/2019 - 06/2016
2Proteins (Proteins, Gene)FDA Link
01/2019 - 08/2009
2resazurinIBA
04/2017 - 01/2013
2Gefitinib (Iressa)FDA Link
02/2017 - 11/2012
2Biological ProductsIBA
06/2016 - 11/2006
2taxaneIBA
03/2016 - 06/2014
2Protein Isoforms (Isoforms)IBA
07/2015 - 02/2014
2AntibodiesIBA
07/2015 - 02/2014
2human ERBB2 proteinIBA
02/2015 - 07/2012
2human KISS1 proteinIBA
02/2014 - 12/2010
2Messenger RNA (mRNA)IBA
07/2012 - 03/2002
2Vascular Endothelial Growth Factor A (Vascular Endothelial Growth Factor)IBA
07/2011 - 03/2006
2ElementsIBA
04/2010 - 08/2009
2Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA
04/2010 - 08/2009
2MelatoninIBA
04/2010 - 08/2009
2Melatonin Receptors (Melatonin Receptor)IBA
04/2010 - 08/2009
2OsteoprotegerinIBA
06/2008 - 09/2003
2Epidermal Growth Factor (EGF)IBA
11/2006 - 10/2005
1GTP Phosphohydrolases (GTPases)IBA
12/2020
1rho GTPase-activating proteinIBA
12/2020
1Zinc Finger E-box-Binding Homeobox 1IBA
10/2020
1ProteomeIBA
10/2020
1Protein-Lysine 6-Oxidase (Lysyl Oxidase)IBA
10/2020
1betaIG-H3 protein (keratoepithelin)IBA
10/2020
1Connective Tissue Growth FactorIBA
10/2020
1Selective Estrogen Receptor Modulators (SERM)IBA
09/2020
1Lactic Acid (Lactate)FDA LinkGeneric
01/2020
1Glucose (Dextrose)FDA LinkGeneric
01/2020
1Adenosine Triphosphate (ATP)IBA
07/2019
1Somatotropin Receptors (Growth Hormone Receptor)IBA
06/2018
1pegvisomantFDA LinkGeneric
06/2018
1ErbB Receptors (EGF Receptor)IBA
01/2018
1Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
01/2018
1Metformin (Glucophage)FDA LinkGeneric
04/2017
1Trastuzumab (Herceptin)FDA Link
02/2017
1S100 Calcium-Binding Protein A4IBA
06/2016
1temsirolimusFDA Link
03/2016
1Estriol (Epiestriol)IBA
12/2014
1liposomal doxorubicin (Doxil)FDA Link
06/2014
1Topotecan (Hycamtin)FDA LinkGeneric
06/2014

Therapy/Procedure

23Therapeutics
06/2021 - 03/2002
13Drug Therapy (Chemotherapy)
12/2019 - 09/2002
7Aftercare (After-Treatment)
11/2018 - 09/2002
5Lymph Node Excision (Lymph Node Dissection)
01/2021 - 08/2010
5Radiotherapy
01/2019 - 05/2005
4Adjuvant Radiotherapy
12/2019 - 05/2005
3Hysterectomy
01/2021 - 03/2002
2Estrogen Replacement Therapy
11/2005 - 09/2003
1Brachytherapy
01/2019
1Palliative Care (Palliative Therapy)
11/2018